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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPHB2
All Species:
0
Human Site:
S586
Identified Species:
0
UniProt:
P29323
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P29323
NP_004433.2
1055
117493
S586
D
K
L
Q
H
Y
T
S
G
H
M
T
P
G
M
Chimpanzee
Pan troglodytes
P0C0K6
1020
110674
A565
Q
V
R
A
R
T
A
A
G
H
G
P
Y
G
G
Rhesus Macaque
Macaca mulatta
XP_001115263
984
109811
L541
E
L
R
E
Q
L
P
L
I
A
G
S
A
A
A
Dog
Lupus familis
XP_852978
963
107419
L520
S
I
Q
E
K
L
P
L
I
I
G
S
S
A
A
Cat
Felis silvestris
Mouse
Mus musculus
P54763
994
110742
K548
Y
Q
T
S
I
K
E
K
L
P
L
I
V
G
S
Rat
Rattus norvegicus
P09759
984
109865
L541
E
L
R
E
Q
L
P
L
I
A
G
S
A
A
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P28693
1004
111945
V559
G
L
V
F
L
I
A
V
V
V
I
I
I
V
C
Frog
Xenopus laevis
Q91571
985
110086
P542
S
E
L
R
E
Q
L
P
L
T
G
S
A
A
A
Zebra Danio
Brachydanio rerio
O13146
981
109636
V538
S
H
E
D
M
L
A
V
G
D
P
N
Q
Q
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
46.1
68.9
90.9
N.A.
92.5
68.9
N.A.
N.A.
89
66.4
51.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
63.7
81.1
91.1
N.A.
92.9
81.1
N.A.
N.A.
91.6
78.8
69.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
20
0
0
N.A.
6.6
0
N.A.
N.A.
0
6.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
26.6
20
13.3
N.A.
20
20
N.A.
N.A.
13.3
26.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
12
0
0
34
12
0
23
0
0
34
45
45
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% C
% Asp:
12
0
0
12
0
0
0
0
0
12
0
0
0
0
0
% D
% Glu:
23
12
12
34
12
0
12
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
12
0
0
0
0
0
0
0
34
0
56
0
0
34
12
% G
% His:
0
12
0
0
12
0
0
0
0
23
0
0
0
0
0
% H
% Ile:
0
12
0
0
12
12
0
0
34
12
12
23
12
0
0
% I
% Lys:
0
12
0
0
12
12
0
12
0
0
0
0
0
0
0
% K
% Leu:
0
34
23
0
12
45
12
34
23
0
12
0
0
0
0
% L
% Met:
0
0
0
0
12
0
0
0
0
0
12
0
0
0
12
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% N
% Pro:
0
0
0
0
0
0
34
12
0
12
12
12
12
0
0
% P
% Gln:
12
12
12
12
23
12
0
0
0
0
0
0
12
12
0
% Q
% Arg:
0
0
34
12
12
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
34
0
0
12
0
0
0
12
0
0
0
45
12
0
12
% S
% Thr:
0
0
12
0
0
12
12
0
0
12
0
12
0
0
12
% T
% Val:
0
12
12
0
0
0
0
23
12
12
0
0
12
12
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
12
0
0
0
0
12
0
0
0
0
0
0
12
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _